As the Product Manager for the Orion SCOM Management Pack I can tell you that we have a fair number of customers with significantly larger deployments of Orion using the SCOM Management Pack to satisfy the very same use case you describe with great success. In the only scenario I've seen to date where scale/size has been an issue, it has been the SCOM database server that has proven the bottleneck, not the Orion SCOM Management Pack.
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